Silvia DeSilva is planning to file a medical malpractice lawsuit against King Edward VII Memorial Hospital and Brighan and Women’s Hospital in Boston after she was given a gadolinium-based contrast agent in preparation for an MRI. DeSilva is a kidney dialysis patient who contracted the painful and potentially fatal condition known as nephrogenic systemic fibrosis (NSF) as a result of the contrast agent.
In 2006 and 2007, the FDA issued warning to healthcare professionals that gadolinium-based contrast agents used in MRI procedures significantly increase the risk of NSF, especially in patients with known kidney problems. The FDA warnings resulted in a black box warning for all gadolinium-based contrast agents. The black box warning is the most severe warning issued by the FDA.
In spite of the warning and Mrs. DeSilva’s known kidney problems, the hospital administered the contrast agent resulting in her NSF condition. NSF is associated with a hardening and thickening of the skin tissue as well as internal organs. There is no known cure for the progressive disorder.